Meet the Opponent: San Francisco 49ers

Head Coach Kyle Shanahan

Offensive Coordinator: Mike McDaniel

Defensive Coordinator: DeMeco Ryans

Special Teams Coordinator: Richard Hightower

WR Brandon Alyuk

Backed up by Mohamed Sanu Sr., Jauan Jennings and Jalen Hurd

LT Trent Williams

Backed up by Jaylon Moore and Shon Coleman

LG Laken Tomlinson

C Alex Mack

Backed up by Jake Brendel

RG Daniel Brunskill

Backed up by Aaron Banks

RT Mike McGlinchey

Backed up by Tom Compton

TE George Kittle

Backed up by Ross Dwelley and Charlie Woerner

WR Deebo Samuel

Backed up by Trent Sherfield

RB Raheem Mostert

Backed up by Trey Sermon, JayMycal Hasty and Elijah Mitchell

FB Kyle Juszczyk

QB Jimmy Garoppolo

Backed up by Trey Lance

LDE Arik Armstead

Backed up by Dee Ford

LDT Javon Kinlaw

Backed up by Kentavius Street and Darrion Daniels

RDT D.J. Jones

Backed up by Kevin Givens and Zach Kerr

RDE Nick Bosa

Backed up by Samson Ebukam and Arden Key

SAM Azeez Al-Shaair

Backed up by Demetrius Flannigan-Fowles

MIKE Fred Warner

WILL Dre Greenlaw

Backed up by Marcell Harris

LCB Emmanuel Moseley

Backed up by Ambry Thomas and Deommodore Lenoir

RCB Jason Verrett

NB K'Waun Williams

FS Jimmie Ward

SS Tavon Wilson

Backed up by Talanoa Hufanga

P/H Mitch Wishnowsky

K Robbie Gould

PR Brandon Alyuk

KOR Elijah Mitchell

LS Taybor Pepper