SANTA CLARA, Calif. – The first victory of the Matt Patricia era will have to wait at least another week as the Lions dropped their second straight contest to start the season, falling to the 49ers on the road Sunday 30-27.
After falling behind by 17 points in the second half, the Lions made a valiant late comeback effort, and had the chance to either tie or take the lead with a drive starting at their 16-yard line with 1:08 left in the game and trailing by three.
But Stafford was unable to convert a 4th and 2 at the Lions' 39-yard line with 21 seconds left, and the comeback came up short. A drop by Lions running back Theo Riddick on third down would have been a first down and turned out to be a killer for the Lions.
As was the case last week in the lopsided loss to the Jets, all three phases played a role in Sunday's defeat.
The defense gave up too many chunk plays, the special teams allowed a long kickoff return that set up a touchdown, and the offense didn't make enough big plays of their own early and late to make up the difference.
Two third quarter 49ers touchdowns, one on a 66-yard run by Matt Breida, and the other a 11-yard pass from quarterback Jimmy Garoppolo to tight end Garrett Celek gave San Francisco their big third-quarter cushion. The Celek touchdown was set up by a 75-yard kickoff return.
Stafford brought the Lions back with two fourth-quarter touchdown passes to Marvin Jones. Jr. and Michael Roberts – he also threw one to Kenny Golladay in the first half – but it was too little too late.
View in-game photos from the Detroit Lions Week 2 game against the San Francisco 49ers.
Detroit Lions captains during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions Tight end Levine Toilolo (87) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions Tight end Luke Willson (82) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Dee Virgin (30) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Darius Slay (23) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive end Romeo Okwara (95) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive back Quandre Diggs (28) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive lineman Da'Shawn Hand (93) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Devon Kennard (42) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Eli Harold (57) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Devon Kennard (42) sacks San Francisco 49ers quarterback Jimmy Garoppolo (10) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Miles Killebrew (35) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Miles Killebrew (35) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Charles Washington (45) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Theo Riddick (25) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Theo Riddick (25) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Theo Riddick (25) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back LeGarrette Blount (29) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) catches a 30-yard touchdown pass during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) catches a 30-yard touchdown pass during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) catches a 30-yard touchdown pass during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) celebrates a 30-yard touchdown catch during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
San Francisco 49ers cornerback Richard Sherman (25) during a NFL football game against the Detroit Lions on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Kerryon Johnson (33) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions center/guard Graham Glasgow (60) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Golden Tate (15) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions offense breaks the huddle during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions head coach Matt Patricia on the sideline during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions tackle Rick Wagner (71) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions offensive lineman Frank Ragnow (77) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Glover Quin (27) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Jarrad Davis (40) sacks San Francisco 49ers quarterback Jimmy Garoppolo (10) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Jarrad Davis (40) sacks San Francisco 49ers quarterback Jimmy Garoppolo (10) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Jalen Reeves-Maybin (44) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Devon Kennard (42) sacks San Francisco 49ers quarterback Jimmy Garoppolo (10) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Devon Kennard (42) sacks San Francisco 49ers quarterback Jimmy Garoppolo (10) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Devon Kennard (42) sacks San Francisco 49ers quarterback Jimmy Garoppolo (10) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Devon Kennard (42) celebrates a sack during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions tackle Rick Wagner (71) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) avoids the rush during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Theo Riddick (25) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back LeGarrette Blount (29) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions tackle Taylor Decker (68) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back LeGarrette Blount (29) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back LeGarrette Blount (29) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) points at the line of scrimmage during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions center/guard Graham Glasgow (60) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions tackle Taylor Decker (68) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back LeGarrette Blount (29) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Jarrad Davis (40) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive tackle Ricky Jean Francois (97) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Glover Quin (27) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive end Romeo Okwara (95) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Devon Kennard (42) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back LeGarrette Blount (29) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Marvin Jones Jr. (11) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) catches a 30-yard touchdown pass during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) catches a 30-yard touchdown pass during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) catches a 30-yard touchdown pass during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) catches a 30-yard touchdown pass during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) catches a 30-yard touchdown pass during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Eli Harold (57) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Teez Tabor (31) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Tavon Wilson (32) makes a special teams tackle during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions head coach Matt Patricia during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions head coach Matt Patricia during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive tackle Ricky Jean Francois (97) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Darius Slay (23) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive lineman Da'Shawn Hand (93) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive lineman Da'Shawn Hand (93) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive lineman Da'Shawn Hand (93) celebrates a stop during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Kerryon Johnson (33) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions kicker Matt Prater (5) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Eli Harold (57) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Jarrad Davis (40) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive tackle Sylvester Williams (92) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Devon Kennard (42) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Teez Tabor (31) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Teez Tabor (31) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Teez Tabor (31) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Teez Tabor (31) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Glover Quin (27) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Kerryon Johnson (33) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Tavon Wilson (32) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Darius Slay (23) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Darius Slay (23) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Kerryon Johnson (33) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back LeGarrette Blount (29) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive tackle A'Shawn Robinson (91) rushes the passer during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Eli Harold (57) sacks San Francisco 49ers quarterback Jimmy Garoppolo (10) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Eli Harold (57) celebrates a sack during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Eli Harold (57) celebrates a sack during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive tackle Sylvester Williams (92) and Detroit Lions defensive tackle A'Shawn Robinson (91) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions offensive lineman Frank Ragnow (77) and Detroit Lions tackle Taylor Decker (68) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions center/guard Graham Glasgow (60) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions offensive huddle during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Marvin Jones Jr. (11) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions kicker Matt Prater (5) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions kicker Matt Prater (5) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions fan during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) at the line of scrimmage during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions tackle Taylor Decker (68) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back LeGarrette Blount (29) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions Tight end Levine Toilolo (87) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive end Romeo Okwara (95) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions center/guard Graham Glasgow (60) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions fullback Nick Bellore (43) and Detroit Lions safety Tavon Wilson (32) on special teams during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Glover Quin (27) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions offensive lineman Frank Ragnow (77) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back LeGarrette Blount (29) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) catches a 30-yard touchdown during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Eli Harold (57) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Glover Quin (27) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions tackle Taylor Decker (68) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions head coach Matt Patricia during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive lineman Da'Shawn Hand (93) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Jamal Agnew (39) fields a punt during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Eli Harold (57) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Tavon Wilson (32) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Marvin Jones Jr. (11) catches a touchdown pas during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Jamal Agnew (39) fields a punt during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Jamal Agnew (39) returns a punt during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Kerryon Johnson (33) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Theo Riddick (25) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Theo Riddick (25) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Glover Quin (27) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Kerryon Johnson (33) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Marvin Jones Jr. (11) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions offensive lineman Frank Ragnow (77) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions center/guard Graham Glasgow (60) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Kerryon Johnson (33) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions offensive lineman Frank Ragnow (77) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions guard Kenny Wiggins (79) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions fullback Nick Bellore (43) and Detroit Lions long snapper Don Muhlbach (48) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions punter Sam Martin (6) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
NFL referee Shawn Hochuli during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions tackle Rick Wagner (71) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Nevin Lawson (24) celebrates a pass breakup during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Jamal Agnew (39) returns a punt during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Golden Tate (15) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Golden Tate (15) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Golden Tate (15) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Golden Tate (15) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Golden Tate (15) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Golden Tate (15) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Jarrad Davis (40) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Jarrad Davis (40) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Jarrad Davis (40) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Glover Quin (27) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver TJ Jones (13) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Jamal Agnew (39) returns a punt during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Jamal Agnew (39) returns a punt during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Jamal Agnew (39) returns a punt during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Jamal Agnew (39) returns a punt during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Golden Tate (15) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions kicker Matt Prater (5) and Detroit Lions long snapper Don Muhlbach (48) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Glover Quin (27) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Dee Virgin (30) and Detroit Lions defensive back Quandre Diggs (28) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Theo Riddick (25) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions punter Sam Martin (6) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Nevin Lawson (24) breaks up a pass during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Darius Slay (23) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Kenny Golladay (19) picks up a first down during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions center/guard Graham Glasgow (60) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Kerryon Johnson (33) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Kerryon Johnson (33) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions punter Sam Martin (6) kicks off during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Dee Virgin (30) on special teams during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Dee Virgin (30) makes a special-teams tackle during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Jarrad Davis (40) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive tackle Sylvester Williams (92) and the defense during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Jamal Agnew (39) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive back Quandre Diggs (28) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Devon Kennard (42) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive end Romeo Okwara (95), Detroit Lions defensive tackle A'Shawn Robinson (91) and Detroit Lions defensive lineman Da'Shawn Hand (93) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Devon Kennard (42) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Jamal Agnew (39) breaks up a pass during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions Tight end Luke Willson (82) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Kerryon Johnson (33) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions tackle Rick Wagner (71) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions fullback Nick Bellore (43) on special teams during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) points out an adjustment to his wide receiver during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) points out an adjustment to his wide receiver during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Golden Tate (15) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Charles Washington (45) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Miles Killebrew (35) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions head coach Matt Patricia during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Jamal Agnew (39) returns a punt during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Kerryon Johnson (33) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions defensive back Tracy Walker (47) returns an interception that would be nullified due to penalty during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Devon Kennard (42) sacks San Francisco 49ers quarterback Jimmy Garoppolo (10) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Devon Kennard (42) sacks San Francisco 49ers quarterback Jimmy Garoppolo (10) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions linebacker Eli Harold (57) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) throws a deep pass during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions quarterback Matthew Stafford (9) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions fans during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back Theo Riddick (25) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Marvin Jones Jr. (11) catches a touchdown pass during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Marvin Jones Jr. (11) catches a touchdown pass during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions offense during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions Tight end Michael Roberts (80) catches a touchdown pass during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions running back LeGarrette Blount (29) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Marvin Jones Jr. (11) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Golden Tate (15) lunges for a first down during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Golden Tate (15) lunges for a first down during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions tackle Taylor Decker (68) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions guard Kenny Wiggins (79) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions long snapper Don Muhlbach (48) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Golden Tate (15) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Jamal Agnew (39) returns a punt during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions wide receiver Golden Tate (15) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions punter Sam Martin (6) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions cornerback Teez Tabor (31) makes a special teams tackle during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
Detroit Lions safety Glover Quin (27) during a NFL football game against the San Francisco 49ers on Sunday, Sept. 16, 2018 in Santa Clara, Calif. (Detroit Lions via AP).
QB Comparison: Both Stafford and Garoppolo were pretty efficient in this one.
Stafford finished the game completing 34 of his 53 pass attempts for 347 yards and three touchdowns. He also lost a fumble. He had a passer rating of 101.7.
Garoppolo was 18-of-26 passing for 206 yards and a couple of scores. He finished the game with a passer rating of 118.4.
Run defense: After giving up 169 yards on the ground to the Jets last week, the Lions allowed 190 to the 49ers on Sunday.
The Jets hit the Lions for a long 62-yard touchdown on a stretch play to the right a week ago. Breida's 62-yarder Sunday was on a similar play.
Ejection: Lions running back LeGarrette Blount was ejected from the game in the fourth quarter after coming off the bench to retaliate for what he thought was a late hit on Stafford after a scramble.
Blount shoved 49ers linebacker Elijah Lee to the ground and was booted from the game.
Strange call: A second and goal play for the 49ers was blown dead early in the second quarter for what umpire Roy Ellison described as an official not being in position to officiate.
After a run on first down, the 49ers quickly lined up to run a play on second down. After setting the ball for play, 49ers center Weston Richburg snapped the ball before the official could get back to his spot behind the formation.
San Francisco head coach Kyle Shanahan was visibly upset and let the officials know it. It all worked out for the 49ers, however, as their next play was a 4-yard touchdown pass.
Dialing up pressure: Credit the Lions' defense for not letting the inactive status of their best pass rusher, Ziggy Ansah, limit their ability to put pressure on Garoppolo.
Linebackers Jarrad Davis, Devon Kennard, Eli Harold and Christian Jones all recorded sacks in the first half.
The Lions weren't able to generate the same kind of pressure in the second half, but they did get two more from both Davis and Kennard.
Injury report: Lions All-Pro cornerback Darius Slay left the game in the third quarter after taking a helmet-to-helmet hit initiated by fullback Kyle Juszczyk on a short third-down completion. No penalty was called on the play.
Slay was diagnosed with a concussion and did not return. His availability for next week's Sunday night game in Detroit against the New England Patriots will be something to monitor this week.
Riddick left the game in the fourth quarter with an ankle injury, but did return.
